Infinite Regress is a theory often criticised by philosophers that aims to explain the cause of existence and time. The theory of Infinite Regress suggests that time has been in an eternal cycle that possesses neither beginning nor end, and due to this it does not require an efficient cause.
The Five Ways are entirely against the theory of Infinite Regress, primarily due to it arguing entirely against the point - The Five Ways insist that there is an efficient cause that started the cycle, and that caused is God.
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Aquinas' Five Ways